About the Disease
Osteoarthritis (OA) is a degenerative joint disease in which cartilage (the protective tissue covering the ends of bones in joints) breaks down over time. This causes pain, stiffness, swelling, decreased mobility, and sometimes joint deformity. Conventional treatments manage symptoms (painkillers, physical therapy, injections, or joint replacement surgery), but do not reverse damage. Stem cell therapy aims to help by regenerating cartilage, reducing inflammation, restoring joint function, and possibly slowing or reversing the degeneration.
Institutes / Trials Offering Stem Cell Therapy for Osteoarthritis
Here are several clinics and research trials working on stem-cell-based treatments for OA / joint pain:
- IRM Hospital – Islamabad, Pakistan
- Offers stem cell therapy for osteoarthritis: harvesting patient’s own stem cells (from fat or bone marrow), concentrating them, and injecting into affected joint to relieve pain and improve mobility. IRMSC
- Abu Dhabi Department of Health, in collaboration with Cellcolabs & Burjeel Holdings – Abu Dhabi, UAE
- Completed a Phase I/II clinical trial (StromaForte) for knee osteoarthritis. Single injection of 50 million mesenchymal stem cells showed safety and reduced pain with improved quality of life. MedPath
- UCI Health / UCI Alpha Clinic – Irvine, California, USA
- Running a Phase 1/2a clinical trial of “IMM01-STEM” therapy to test safety/tolerability in patients aged 50-75 with knee osteoarthritis. Also investigating prevention of muscle atrophy around the knee joint. UCI Health+1
- OrthoHealing Center (USA) – California, USA
- Participating in a multicenter clinical trial using adipose (fat-derived) stem cells (patient’s own fat) to treat knee osteoarthritis. The trial includes treatment, follow-ups, and planning for cell storage. THE ORTHOHEALING CENTER
- Personalized Stem Cells, Inc. – USA (multiple sites: San Diego CA, Los Angeles CA, Portland OR, Chicago IL, New Jersey)
- Conducting an FDA-approved clinical trial (IND) using adipose-derived stem cells in knee osteoarthritis (PSC-CP-001). Enrolling many patients to evaluate safety & efficacy. Personalized Stem Cells
- Stem Cells Center – Malaysia
- Offers joint injections using mesenchymal stem cells or exosomes for knees, hips, shoulders etc. They treat OA with regenerative, non-surgical approaches. Premium Stem Cells Malaysia
- RCERT SDN BHD (Regional Cell Research & Therapy Centre) – Kuala Lumpur, Malaysia
- Provides osteoarthritis therapy by MSCs, exosomes; personalized protocols. Joint pain relief, mobility improvement are reported. Rcer Therapeutics
- Stem Cell Institute, Panama – Panama City, Panama
- Offers allogeneic umbilical cord tissue derived mesenchymal stem cells treatments for osteoarthritis among other joint disorders. They provide patient follow-up out to 1 year or more. Stem Cell Institute
